Peptide aṣaAkopọIṣẹ
Hangzhou Go Top Peptide Biotech , ti iṣeto ni 2014, ni a National High-tekinoloji Enterpriseamọja ni iwadii, idagbasoke ati iṣelọpọ awọn peptides ati awọn itọsẹ ti o jọmọ.
Ile-iṣẹ naapeptide iwadi aarinLọwọlọwọ wa ni agbegbe Qiantangof Hangzhou, ti o bo agbegbe ti o ju awọn mita mita 3,000 lọ.Awọnile-iṣẹ's ile-iṣẹ wa ni No.24, Haitian Road, Shangyu District, Shaoxing ilu, Zhejiang ekun.Nibẹ ni o wa tun meji ifowosowopo eweko, ọkan jẹ funowo peptide GMP iṣelọpọ be niAgbegbe Anji ti agbegbe Zhejiang, ọkan jẹ fun API moleku kekere ti o wa ninuYuncheng ilu ti Shanxi ekun.A dia okeerẹ ga-tekinoloji kekeke, iṣakojọpọ iwadi, iwọn-pilot, iṣowo ati awọn tita agbaye.
Ile-iṣẹ naa nilori100awọn oṣiṣẹ,o si nini idagbasoke diẹ ẹ sii ju40 ogbo elegbogipeptides,ju lọ10 awọn iwe-kikanti ni aṣẹ.To lododun gbóògì agbarais titi di100 kilo, awọn nọmba ti aṣa peptides ni o ni ti de loke 20,000.A le pese awọn iṣẹ peptide ọkan-iduro lati iwadi (mg) si iṣowo (KGs).
Peptide Iyipada Akojọ
N-awọn iyipada ebute
| {N-Me-Ala} | {N-Me-Asp} | {N-Me-Glu} | {N-Me-Ile} |
| {N-Me-Leu} | {N-Me-Pade} | {N-Me-Nle} | {N-Me-Nva} |
| {N-Me-Phe} | {N-Me-Ser} | {N-Me-Thr} | {N-Me-Tyr} |
| {N-Me-Val} | {Sar} | N-Me-Arg | N-Me-Asn |
| N-Me-beta-Ala | N-Me-Gln | N-Me-Lys | N-Me-Trp |
C-awọn iyipada ebute
| {Afara Mono Disulfide} | {Afara Disulfide Meji} | {Afara Disulfide Meta} |
| {Afara Disulfide ID} | {Abala kanna.Inter-Disulfide Afara } | {Orisirisi Inter-Disulfide Afara} |
| {Amide cyclic (opin)} | {Amide cyclic (Ẹwọn ẹgbẹ)} | {Orn ẹgbẹ pq Amide cyclic} |
| {Thioester cyclic} | {lactone cyclic} | {Ayika-aaya} |
Amino acids dani
| {2-Aze} | {3-Aze} | {5,5-Dime-Pro} |
| {5-ASA} | {Abu} | {Ac-Lys} |
| {Aib} | {Beta-Asp} | {Bpa} |
| {Cha} | {Chg} | {Cit} |
| {Cpg} | {Cys(Acm)} | {Cys(Bzl)} |
Isotope aami peptides
| Lys(13C6,15N2) | Ile(13C6,15N) |
| Leu(13C6,15N) | Val(13C5, 15N) |
| Arg (13C6, 15N4) |
Awọn iyipada peptide Fuluorisenti / awọn orisii FRET
| Biotin- | Dansyl- | peptide fluorecent ti parun |
| Biotin-Ahx- | Dansyl-Ahx- | Dabcyl |
| 5-FAM- | Cy3- | Dabcyl / Glu (Edans) -NH2 |
| 5-FAM-Ahx- | Cy5- | Dansyl- |
| FITC- | MCA/DNP | Dansyl-Ahx- |
| FITC-Ahx- | AMC | Edans / Dabcyl |
Peptide Conjugates
| BSA (-COOH ti C ebute | KLH(-NH2 ti N ebute) | OVA(-COOH ti ebute C) |
| BSA Conjugation on Cys | KLH Conjugation on Cys | OVA(-NH2 ti N ebute) |
| OVA Conjugation on Cys |
Phosphorylation
| {Ser} | {D-pSer} |
| {pTyr} | {D-pTyr} |
| {pThr} | {D-pThr} |
Awọn iyipada miiran (PEGylation, Awọn iyipada gigun kẹkẹ, Awọn afara Disulfide)
| PEGylation | Awọn iyipada iyipo | Disulfide Bridges |
| {Mini-PEG1} | Ori si iru gigun kẹkẹ | {Afara Mono Disulfide} |
| {Mini-PEG2} | {Afara Disulfide Meji} | |
| {PEG-11} | {Afara Disulfide Meta} | |
| {PEG-12} | {Afara Disulfide ID} | |
| …… | …… | …… |