A finifini ifihan to tidulutide

Ilana iṣe ti tidulutide Gattex (teduglutide)

Teduglutide jẹ afọwọṣe ẹda eniyan ti glucagon-like peptide-2 (GLP-2), peptide kan ti a fi pamọ nipasẹ awọn sẹẹli L ninu ikun jijin.GLP-2 ni a mọ lati mu ilọsiwaju iṣan inu ati iṣan ẹjẹ ọna abawọle ati ṣe idiwọ yomijade acid inu.Fun awọn iwọn ti lu peptide ati peptide receptor 2 glucagon awọn ayẹwo, insulin-bi ifosiwewe idagba ninu awọn sẹẹli endocrine ifun, awọn sẹẹli epithelial ti okun iṣan, submucosa ati myenteric duro laarin awọn iṣan inu inu.Iṣiṣẹ ti awọn olugba wọnyi nfa itusilẹ agbegbe ti ọpọlọpọ awọn media, pẹlu insulin-like growth factor (IGF) 1, cell growth factor formation nitrogen oxide ati cutin cell growth factor (KGF).

Tidulutide, glucagon-like peptide 2 (GLP-2) afọwọṣe, dinku isọfun inu ati iṣelọpọ agbara ati ṣe ilana idagba, ẹda ati imularada awọn sẹẹli ifun inu.Peptide pọ si nọmba lapapọ ti awọn sẹẹli wọnyi, o le mu gbigba ti ifun kekere pọ si, dinku gbuuru.Aisan ifun kukuru ni awọn agbalagba le ṣe itọju ni ile-iwosan.Oogun naa ti di awọn oogun ti a ṣeduro akọkọ si toje ṣugbọn alailagbara pupọ.

A finifini ifihan to tidulutide

Kẹmika molikula agbekalẹ ti tidulutide

Awọn ipilẹ ipilẹ

Orukọ: fun c peptide (Teduglutide)

Nọmba: GT – F027

CAS nọmba: 197922-42-2

Tẹle: His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn- Trp-Leu-Ile-Gln-Thr-Lys- Ile-Thr-Asp

Ilana molikula: C164H252N44O55S

iwuwo molikula: 3752.08248