Dulaglutide, 923950-08-7

Inagijẹulaglutide – ojutu ni PBS/ dulaglutide

CAS No.: 923950-08-7

Ile-iṣẹ No.: GT-F002

Tẹle: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Ala-Lys-Glu-Phe-Ile- Ala-Trp-Leu-Val-Lys-Gly-Gl y-Gly-OH

Ilana molikula: C149H221N37O49

Iwọn molikula: 3314.62

Dulaglutide CAS NỌ.923950-08-7.jpg

Awọn itọkasi imọ-ẹrọ:

Irisi White lulú
Mimọ (HPLC) jẹ ≥95.0%

Heterozygosity ẹyọkan ko kere ju 2.0%

Akoonu acetic acid wa lati 5.0% si 12.0%

Akoonu ọrinrin jẹ ≤10.0%

Akoonu peptide jẹ ≥80.0%

Iṣakojọpọ ati Gbigbe:

Iwọn otutu kekere, iṣakojọpọ igbale, deede si milligram lori ibeere.

Apejuwe ọja:

Durraglutide jẹ agonist tuntun GLP-1R ti n ṣiṣẹ pipẹ, eyiti o jẹyọ lati idapọ ti awọn analogues DPP-4 inhibitory GLP-1 meji ati ajẹkù eruku IgG4-Fc eniyan immunoglobulin.Iṣẹ ṣiṣe rẹ jọra si ti GLP-1 endogenous ni awọn ifihan ile-iwosan, pẹlu igbesi aye idaji ti awọn ọjọ 5, ati pe o le ṣe idaduro imukuro kidirin ni imunadoko.FDA fọwọsi dulaglutide fun abẹrẹ subcutaneous ni Oṣu Kẹsan ọdun 2014. Igbimọ Yuroopu fọwọsi dulaglutide fun abẹrẹ abẹlẹ ni Yuroopu ni Oṣu kejila ọdun 2014.

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